
Activated Silk® KDF-β
A growth factor that rapidly elevates the skin’s natural baseline and restores skin after damage, UV exposure and decline. This peptide supports the natural production of proteins associated with skin resilience, smoothness and hydration, and can lead to a 175% increase in skin regeneration rate.
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Activated Silk® KDF - β
The first peptide designed to fight modern skin stressors.
- Increases natural regeneration rate of skin
- Protects skin from external aggressors and oxidative stressors
- Reduces the appearance of symptoms associated with eczema-prone skin
Today’s environment has introduced new oxidative stressors to our skin, resulting in effects like dullness, hyperpigmentation and accelerated aging. While legacy skincare ingredients like hyaluronic acid, retinol, and vitamin C happen to address some symptoms of oxidative stress, they were not designed specifically for the problem.
Activated Silk® KDF-β is a first-of-its-kind ingredient, developed specifically to help skin adapt to today’s evolving environmental challenges. In a class of its own, this bioactive peptide solution offers greater repair and protection to skin’s epidermal layer by increasing the natural regeneration rate.
Activated Silk® KDF-β supports skin’s natural differentiation, a process that replaces old skin cells with new, vibrant ones. As a result, skin cells spend less time exposed to external aggressors, and skin recovers from damage more quickly.
Increasing the skin's natural regeneration helps to reduce the appearance of dry and flaky skin, skin redness, and the appearance of symptoms associated with eczema-prone skin.
Activated Silk® KDF-β also supports the natural production of beneficial skin health proteins: involucrin for elasticity, filaggrin for hydration, and claudin for skin barrier integrity. Delivering these supportive proteins further helps to strengthen the skin barrier and protect against external aggressors and oxidative stressors.
Overall, Activated Silk® KDF-β increases skin's natural keratinocyte differentiation, for skin rejuvenation that's scientifically proven, more natural and more sustainable.01

Activated Silk® KDF-β Claims
Performance07
- Increases natural regeneration rate of skin
- Reduces the appearance of skin redness
- Reduces the appearance of dry and flaky skin
- Reduces the appearance of symptoms associated with eczema-prone skin
- Supports natural skin-health proteins
- Improves skin barrier integrity
- Safe for sensitive skin
- Gentle for daily use
Sustainability
- Naturally derived
- Sustainable 01
- Biodegradable
- Not formulated with petrochemicals
- Cruelty-free certified
- Made from upcycled materials
- Made from renewable resources
- Made with renewable energy
- Non-GMO
- Supportive of a circular economy
Footnotes
01The manufacturing of Activated Silk® technology contributes to achieving 14/17 U.N. Sustainable Development Goals. For more information, visit sdgs.un.org/goals
02Compared to petrochemical ingredients.
03Activated Silk® peptides are naturally-derived. For more information on NATRUE approvals, see www.natrue.org
04Based on a clinical study of 32 subjects using 2% Activated Silk® 33B-α in a leave-on product over a 28-day use period.
05Based on a clinical study of 19 subjects using 0.5% Activated Silk® 27P-α over a 28-day use period.
06Based on a clinical study of 18 subjects using 0.5% Activated Silk® 8A-α over a 28-day use period.
07Based on a clinical study of 17 subjects using 0.5% Activated Silk® KDF-β over a 2-day use period.
08Not manufactured with PEG or palm ingredients.
09Not manufactured with silicone ingredients.